Imaging built for early decisions.

Imaging Core Lab — Early Phase Clinical Trials

Fidēs is a science-first imaging CRO for Phase I–II programs where imaging actively shapes go / no-go decisions. We align imaging strategy with biology, physiology and study intent, so sponsors have the clarity to act while it still matters.

A different kind of imaging partner

We embed imaging into scientific decision-making from the outset, not as a procedural service, but as an active input into your development strategy.

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Who we are

Fidēs was built for a specific problem in drug development: early- phase programs where imaging is central to understanding biology, and where decisions cannot wait until the end of a study. We embed imaging into scientific decision-making from the outset, not as a procedural service, but as an active input into your development strategy.

Fidēs is a spin-out from Motilent, a decade-long leader in digital imaging infrastructure for gastrointestinal research. That foundation gives us proprietary technology, a strong scientific network, and a track record of delivering meaningful insights in complex, early-phase settings.

Our Company Our Company
Our Company Our Company
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Science-led design

Imaging strategy aligned with biological questions and decision points, not just endpoints to report.

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Real-time visibility

Live access to imaging data, annotations and analyses throughout the study lifecycle via Aperis.

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Scientific integrity

We provide honest, objective feedback, including when findings are uncomfortable. Better decisions require clarity, not reassurance.

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Augmented endpoints

Novel and additive imaging measures that go beyond standard endpoints to characterise treatment response more completely.

From study design
to final report.

We provide comprehensive imaging support across the full lifecycle of early clinical development, with a focus on studies where imaging insight directly informs strategy.

End-to-End Imaging Services
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Aligning imaging strategy with biological questions.

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Developing and reviewing imaging charters and manuals.

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Identifying and qualifying high-quality imaging sites.

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Training and supporting imaging sites throughout the trial.

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Standardizing image collection processes.

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Securely managing data through a digital platform.

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Reviewing and interpreting data by specialists.

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Providing clear and comprehensive reports for decision-making.

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01.
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Study Design

Aligning imaging strategy with biological questions.

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02.
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Study Documentation

Developing and reviewing imaging charters and manuals.

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03.
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Site Selection

Identifying and qualifying high-quality imaging sites.

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Site Management

Training and supporting imaging sites throughout the trial.

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Data Acquisition

Standardizing image collection processes.

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06.
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Data Management

Securely managing data through a digital platform.

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Data Analysis

Reviewing and interpreting data by specialists.

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Final Report

Providing clear and comprehensive reports for decision-making.

Where We Work

Fidēs brings deep scientific knowledge and a growing KOL network to each therapeutic area. Natively strong in GI, and expanding across oncology and beyond.

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Gastroenterology

IBD, motility, hepatic disease

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Oncology

Solid tumours, response assessment

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Women’s Health

Uterine Motility, Endometriosis, Adenomyosis, Uterine and Cervical Cancer, PMOS and infertility

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Rheumatology

Neurology, neurodegeneration

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Systemic and Chronic

CKD, renal function

Aperis Platform

Transparency by design.

Aperis is our proprietary, web-native imaging workflow platform built to support scientific decision-making in early development. Most imaging platforms move data from A to B. Aperis was designed for how scientists actually interrogate imaging while studies are still evolving.

  • Real-time data visibility Sponsors access imaging data, annotations and analyses continuously, not only at formal reporting milestones.

  • Collaborative review environment Multi-modality side-by-side image review with embedded workflows and direct sponsor access.

  • Rapid study setup Standard studies configured within one day, complex studies within days, not weeks.

  • Adaptive imaging support Designed for live studies where strategy may need to evolve as data emerges.

Recent case studies

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The Power of Movement: Motion as an Imaging Endpoint

Augmenting standard MRI endpoints with motility measures to deliver a more complete characterisation of biological response in Crohn's disease.

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Structural and Functional MRI Assessment in Post-Surgical J-Pouch Patients

Combining structural and functional MRI to characterise pouch function and inflammation in post-surgical J-pouch patients.

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Uterine Contractility as a Quantitative Endpoint in Early-Phase Gynaecology Trials

Establishing uterine contractility as a quantitative, reproducible imaging endpoint for early-phase gynaecology trials.

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Beyond RECIST: Additive Imaging Endpoints in Solid Tumour Trials

How augmented endpoint analysis provides earlier and more interpretable signals than standard volumetric measures alone.

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Live Data Visibility in Phase I Imaging Trials

A review of how real-time imaging access changes sponsor behaviour and supports earlier go / no-go decisions in early development.

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Augmented MRI Endpoints in a Phase II Crohn’s Program

Adding functional motility metrics to a Phase II Crohn's imaging protocol to sharpen the read on treatment response.

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Cine-MRI Motility Analysis as a Primary Endpoint

Using cine-MRI motility analysis as a primary endpoint to detect functional change earlier than structural measures alone.

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Our Foundation

Built from Motilent’s platform and science.

10
+

Years of GI imaging science from Motilent

500
+

Research projects and clinical trials on the platform

FDA

Listed imaging platform: EntrolyticsMD

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Therapy areas supported across the Fidēs network

Fidēs is a spin-out from Motilent — a medical imaging software company with over a decade of focused work on quantitative GI imaging, proprietary motion analysis tools and a platform used across more than 500 research projects and clinical trials globally.

That foundation gives Fidēs a mature, clinically validated technology base in Aperis, and native scientific depth in gastroenterology and hepatology. It also gives us a network of leading KOLs who contribute to study design, endpoint development and scientific oversight across therapy areas.

Fidēs is independent and therapy-agnostic. Our focus extends across oncology, cardiovascular, CNS, renal and metabolic disease, with scientific fit, not inherited specialism, guiding where we work.

Work With Us

Ready to discuss
your study?

Whether you are early in study design or scoping an imaging partner for an upcoming trial, we are happy to have a no-obligation conversation about your program.

Get in Touch Get in Touch